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C17ORF67 anticorps

C17ORF67 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7246070
  • Antigène Tous les produits C17ORF67
    C17ORF67 (Chromosome 17 Open Reading Frame 67 (C17ORF67))
    Reactivité
    Humain
    Hôte
    • 7
    Lapin
    Clonalité
    • 7
    Polyclonal
    Conjugué
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C17ORF67 est non-conjugé
    Application
    ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Fusion protein of human C17orf67
    Isotype
    IgG
  • Indications d'application
    IHC 1:40-1:200, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.7 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    C17ORF67 (Chromosome 17 Open Reading Frame 67 (C17ORF67))
    Autre désignation
    C17orf67 (C17ORF67 Produits)
    Synonymes
    anticorps chromosome 17 open reading frame 67, anticorps C17orf67
    Sujet
    C17orf67 (chromosome 17 open reading frame 67) is a 114 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
    UniProt
    Q0P5P2
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