TUBGCP4 anticorps

N° du produit ABIN7004071

Détail du produit anti-TUBGCP4 anticorps

Antigène: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUBGCP4 est non-conjugé

Application: ELISA, Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human TUBGCP4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TUBGCP4

Antigène: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Autre désignation: TUBGCP4 (TUBGCP4 Produits)

Synonymes: anticorps RGD1306924, anticorps 76p, anticorps MGC81229, anticorps zgc:194561, anticorps zgc:194580, anticorps DKFZp459O2210, anticorps 76P, anticorps GCP-4, anticorps GCP4, anticorps h76p, anticorps hGCP4, anticorps hGrip76, anticorps 4932441P04Rik, anticorps D2Ertd435e, anticorps tubulin, gamma complex associated protein 4, anticorps tubulin gamma complex associated protein 4, anticorps tubulin gamma complex associated protein 4 L homeolog, anticorps Tubgcp4, anticorps TUBGCP4, anticorps tubgcp4.L, anticorps tubgcp4

Sujet: This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 76 kDa

UniProt: Q9UGJ1

Pathways: M Phase