MGP anticorps
Aperçu rapide pour MGP anticorps (ABIN7246430)
Antigène
Voir toutes MGP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Fusion protein of human MGP
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Isotype
- IgG
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Indications d'application
- IHC 1:70-1:350, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.32 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MGP (Matrix Gla Protein (MGP))
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Autre désignation
- MGP
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Sujet
- Matrix Gla protein (MGP) is is a vitamin K-dependent,extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP),which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS),which is an autosomal recessive disorder characterized by abnormal cartilage calcification,peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.
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UniProt
- P08493
Antigène
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