C8orf4 anticorps

N° du produit ABIN7246439

Détail du produit anti-C8orf4 anticorps

Antigène: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C8orf4 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human C8orf4

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur C8orf4

Antigène: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Autre désignation: C8orf4 (C8orf4 Produits)

Synonymes: anticorps TC-1, anticorps TC1, anticorps 1110065B09Rik, anticorps AW121743, anticorps AW321058, anticorps C8ORF4, anticorps transcriptional and immune response regulator, anticorps chromosome 22 open reading frame, human C8orf4, anticorps TCIM, anticorps C22H8ORF4, anticorps Tcim

Sujet: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

UniProt: Q9NR00