L’anticorps Lapin Polyclonal anti-PSPC1 a été validé pour ELISA et IHC. Il convient pour détecter PSPC1 dans des échantillons de Humain, Souris et Rat.
PSPC1
Reactivité: Humain, Souris
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC 1:30-1:150, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.54 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
PSPC1
(Paraspeckle Component 1 (PSPC1))
Autre désignation
PSPC1
Sujet
This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.