NIPBL anticorps

N° du produit ABIN7246814

Cet anticorps Lapin Polyclonal détecte spécifiquement NIPBL dans ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour NIPBL anticorps (ABIN7246814)

Antigène: NIPBL (Nipped-B like Protein (NIPBL))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NIPBL est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NIPBL anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human NIPBL

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NIPBL

Antigène: NIPBL (Nipped-B like Protein (NIPBL))

Autre désignation: NIPBL

Sujet: This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: Q6KC79

Pathways: Sensory Perception of Sound, Stem Cell Maintenance