PPM1M anticorps

N° du produit ABIN7247633

Détail du produit anti-PPM1M anticorps

Antigène: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPM1M est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human PPM1M

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.74 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PPM1M

Antigène: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Autre désignation: PPM1M (PPM1M Produits)

Synonymes: anticorps 2810423O19Rik, anticorps AW610647, anticorps C77250, anticorps PP2Ceta, anticorps PP2C-eta, anticorps PP2CE, anticorps protein phosphatase 1M, anticorps protein phosphatase, Mg2+/Mn2+ dependent 1M, anticorps Ppm1m, anticorps PPM1M

Sujet: PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).

UniProt: Q96MI6