SAV1 anticorps

N° du produit ABIN7247840

Cet anticorps anti-SAV1 est un anticorps Lapin Polyclonal détectant SAV1 dans ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SAV1 anticorps (ABIN7247840)

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAV1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SAV1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human SAV1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.32 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SAV1

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Autre désignation: SAV1

Sujet: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

UniProt: Q9H4B6

Pathways: Stem Cell Maintenance