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Foxk1 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement Foxk1 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN7247897

Aperçu rapide pour Foxk1 anticorps (ABIN7247897)

Antigène

Voir toutes Foxk1 Anticorps
Foxk1 (Forkhead Box K1 (Foxk1))

Reactivité

  • 38
  • 27
  • 9
  • 8
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 40
Lapin

Clonalité

  • 40
Polyclonal

Conjugué

  • 29
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Foxk1 est non-conjugé

Application

  • 26
  • 12
  • 12
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Antigen affinity purification

    Immunogène

    Synthetic peptide of human FOXK1

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:2000, ELISA 1:5000-1:10000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.5 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    Foxk1 (Forkhead Box K1 (Foxk1))

    Autre désignation

    FOXK1

    Sujet

    The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 75 kDa

    UniProt

    P85037
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