anticorps ABC42, anticorps ALD, anticorps ALDP, anticorps AMN, anticorps RGD1562128, anticorps zgc:172102, anticorps ABCD1, anticorps Ald, anticorps Aldgh, anticorps ATP binding cassette subfamily D member 1, anticorps ATP-binding cassette, sub-family D (ALD), member 1, anticorps ATP-binding cassette sub-family D member 1, anticorps ATP binding cassette subfamily D member 1 L homeolog, anticorps ABCD1, anticorps Abcd1, anticorps abcd1, anticorps CpipJ_CPIJ013253, anticorps VDBG_05717, anticorps abcd1.L
Sujet
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD),an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.