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HIST1H2BA anticorps

Cet anticorps anti-HIST1H2BA est un anticorps Lapin Polyclonal détectant HIST1H2BA dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7248536

Aperçu rapide pour HIST1H2BA anticorps (ABIN7248536)

Antigène

HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))

Reactivité

Humain, Souris, Rat

Hôte

  • 21
  • 1
Lapin

Clonalité

  • 21
  • 1
Polyclonal

Conjugué

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HIST1H2BA est non-conjugé

Application

Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Antigen affinity purification

    Immunogène

    Synthetic peptide of human HIST1H2BA

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.98 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))

    Autre désignation

    HIST1H2BA

    Sujet

    The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .

    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 14 kDa

    UniProt

    Q96A08
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