KLF1 anticorps
Aperçu rapide pour KLF1 anticorps (ABIN7248551)
Antigène
Voir toutes KLF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Synthetic peptide of human KLF1
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Isotype
- IgG
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Indications d'application
- IHC 1:50-1:100, ELISA 1:2000-1:5000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.96 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
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Autre désignation
- KLF1
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Sujet
- This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.
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UniProt
- Q13351
Antigène
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