IRG1 anticorps

N° du produit ABIN7248602

Détail du produit anti-IRG1 anticorps

Antigène: IRG1 (Immunoresponsive Gene 1 (IRG1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRG1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human ACOD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.32 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IRG1

Antigène: IRG1 (Immunoresponsive Gene 1 (IRG1))

Autre désignation: ACOD1 (IRG1 Produits)

Synonymes: anticorps CAD, anticorps AI323667, anticorps aconitate decarboxylase 1, anticorps ACOD1, anticorps Acod1

Sujet: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 53 kDa

UniProt: A6NK06