DOK3 anticorps

N° du produit ABIN7249172

Détail du produit anti-DOK3 anticorps

Antigène: DOK3 (Docking Protein 3 (DOK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK3 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human DOK3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:1000-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DOK3

Antigène: DOK3 (Docking Protein 3 (DOK3))

Autre désignation: DOK3 (DOK3 Produits)

Synonymes: anticorps DOK3, anticorps DOKL, anticorps AI450713, anticorps Dokl, anticorps docking protein 3, anticorps DOK3, anticorps Dok3

Sujet: DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 53 kDa

UniProt: Q7L591