ZBTB10 anticorps

N° du produit ABIN7249292

Cet anticorps Lapin Polyclonal détecte spécifiquement ZBTB10 dans WB et ELISA. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour ZBTB10 anticorps (ABIN7249292)

Antigène: ZBTB10 (Zinc Finger and BTB Domain-Containing Protein 10 (ZBTB10))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB10 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ZBTB10 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human ZBTB10

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:2000-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZBTB10

Antigène: ZBTB10 (Zinc Finger and BTB Domain-Containing Protein 10 (ZBTB10))

Autre désignation: ZBTB10

Sujet: RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98 % homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 95 kDa

UniProt: Q96DT7