CREBZF anticorps

N° du produit ABIN7249328

Détail du produit anti-CREBZF anticorps

Antigène: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREBZF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human CREBZF

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CREBZF

Antigène: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Autre désignation: CREBZF (CREBZF Produits)

Synonymes: anticorps SMILE, anticorps ZF, anticorps 1110034C16Rik, anticorps 6330417B10Rik, anticorps LAZip, anticorps LAZipII, anticorps Zf, anticorps RGD1565584, anticorps CREB/ATF bZIP transcription factor, anticorps CREBZF, anticorps Crebzf

Sujet: Host cell factor (HCF) is a cellular cofactor required for the activation of VP16 which expresses the herpes simplex virus immediate early gene. V16 binds to HCF through a 4-amino acid motif similar to the HCF binding domain of the basic leucine-zipper proteins Luman and Zhangfei (ZF). Luman activates promoters containing cAMP or unfolded protein response elements (UPRE). Zhangfei suppresses the transcriptional activity of Luman, but requires HCF binding which may target Luman and Zhangfei to a common location. Sequence analysis predicts that the deduced 272-amino acid Zhangfei protein has a negatively charged N terminus, a leucine zipper of 6 heptad leucine repeats separated by a conserved 6-amino acid spacer, a basic domain, and a bZIP region. It is also presumed that the N-terminal acidic region of Zhangfei is an activation domain.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 37 kDa

UniProt: Q9NS37