CD1a anticorps
Aperçu rapide pour CD1a anticorps (ABIN7250218)
Antigène
Voir toutes CD1a AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Monoclonal Antibody
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Purification
- Protein A purification
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Immunogène
- Synthetic Peptide
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Isotype
- IgG
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Indications d'application
- IHC 1:100-1:300, IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD1a
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Autre désignation
- CD1A
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Sujet
- This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
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UniProt
- P06126
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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