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beta Catenin anticorps

CATNB Reactivité: Humain, Souris, Rat WB, IF, IHC (p) Hôte: Souris Monoclonal 2E4 unconjugated
N° du produit ABIN7250260
  • Antigène Voir toutes beta Catenin (CATNB) Anticorps
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    Reactivité
    • 330
    • 247
    • 225
    • 29
    • 23
    • 22
    • 18
    • 18
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 271
    • 58
    • 4
    • 2
    • 1
    Souris
    Clonalité
    • 266
    • 70
    Monoclonal
    Conjugué
    • 122
    • 22
    • 16
    • 15
    • 15
    • 15
    • 15
    • 15
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Cet anticorp beta Catenin est non-conjugé
    Application
    • 206
    • 158
    • 120
    • 118
    • 74
    • 62
    • 61
    • 48
    • 35
    • 31
    • 22
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Attributs du produit
    Monoclonal Antibody
    Purification
    Protein A purification
    Immunogène
    Recombinant Protein
    Clone
    2E4
    Isotype
    IgG
    Top Product
    Discover our top product CATNB Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    Autre désignation
    Catenin beta (CATNB Produits)
    Synonymes
    anticorps Bfc, anticorps Catnb, anticorps Mesc, anticorps CTNNB, anticorps MRD19, anticorps armadillo, anticorps ctnnb, anticorps id:ibd2058, anticorps wu:fb73e10, anticorps wu:fi81c06, anticorps wu:fk25h01, anticorps beta-catenin, anticorps ctnnb1, anticorps CHBCAT, anticorps catenin (cadherin associated protein), beta 1, anticorps catenin beta 1, anticorps catenin (cadherin-associated protein), beta 1, anticorps catenin beta 1 L homeolog, anticorps Ctnnb1, anticorps CTNNB1, anticorps ctnnb1, anticorps ctnnb1.L
    Sujet
    Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
    Poids moléculaire
    92 kDa
    UniProt
    P35222
    Pathways
    Peptide Hormone Metabolism
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