Cet anticorps anti-Active CASP3 Monoclonal Souris (Clone 5A2) (ABIN7250272) détecte spécifiquement Active CASP3 dans IF, IHC (p) et WB.
L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
Active CASP3
Sujet
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.