TTR anticorps
Aperçu rapide pour TTR anticorps (ABIN7250359)
Antigène
Voir toutes TTR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Monoclonal Antibody
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Purification
- Protein A purification
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Immunogène
- Recombinant Protein of TTR
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000, IHC 1:50-300
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TTR (Transthyretin (TTR))
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Autre désignation
- TTR
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Sujet
- This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
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Poids moléculaire
- 16 kDa
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UniProt
- P02766
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Pathways
- Hormone Transport
Antigène
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