CASP4 p20 (Cleaved-Gln81) anticorps

N° du produit ABIN7251298

Cet anticorps anti-CASP4 p20 est un anticorps Polyclonal produit chez le Lapin, détectant CASP4 p20 dans ELISA, IHC (p) et WB. Convient pour Humain.

Aperçu rapide pour CASP4 p20 (Cleaved-Gln81) anticorps (ABIN7251298)

Antigène: CASP4 p20

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Détail du produit

Épitope: Cleaved-Gln81

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human Caspase-4 p20

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: CASP4 p20

Sujet: This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.

Poids moléculaire:

Observed_MW: 43+22 kDa

Calculated_MW: 43 kDa

UniProt: P49662