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VRK1 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement VRK1 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN7252186

Aperçu rapide pour VRK1 anticorps (ABIN7252186)

Antigène

Voir toutes VRK1 Anticorps
VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reactivité

  • 49
  • 10
  • 4
Humain, Souris

Hôte

  • 41
  • 8
Lapin

Clonalité

  • 43
  • 6
Polyclonal

Conjugué

  • 24
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp VRK1 est non-conjugé

Application

  • 41
  • 14
  • 13
  • 13
  • 9
  • 8
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Antigen affinity purification

    Immunogène

    Fusion protein of human VRK1

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    VRK1 (Vaccinia Related Kinase 1 (VRK1))

    Autre désignation

    VRK1

    Sujet

    This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 45 kDa

    UniProt

    Q99986
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