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CNOT7 anticorps

Cet anticorps anti-CNOT7 est un anticorps Lapin Polyclonal détectant CNOT7 dans ELISA et IHC. Adapté pour Humain et Souris.
N° du produit ABIN7253965

Aperçu rapide pour CNOT7 anticorps (ABIN7253965)

Antigène

Voir toutes CNOT7 Anticorps
CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivité

  • 39
  • 19
  • 8
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Humain, Souris

Hôte

  • 32
  • 7
Lapin

Clonalité

  • 33
  • 6
Polyclonal

Conjugué

  • 24
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CNOT7 est non-conjugé

Application

  • 31
  • 21
  • 14
  • 13
  • 7
  • 3
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Antigen affinity purification

    Immunogène

    Fusion protein of human CNOT7

    Isotype

    IgG
  • Indications d'application

    IHC 1:50-1:100, ELISA 1:5000-1:10000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.96 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

    Autre désignation

    CNOT7

    Sujet

    The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CNOT8.

    UniProt

    Q9UIV1

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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