ASNA1 anticorps
Aperçu rapide pour ASNA1 anticorps (ABIN7254112)
Antigène
Voir toutes ASNA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Fusion protein of human ASNA1
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Isotype
- IgG
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Indications d'application
- IHC 1:50-1:200, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.26 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))
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Autre désignation
- ASNA1
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Sujet
- ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.
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UniProt
- O43681
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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