VNN1 anticorps
Aperçu rapide pour VNN1 anticorps (ABIN7254229)
Antigène
Voir toutes VNN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogène
- Synthetic peptide of human VNN1
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Isotype
- IgG
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Indications d'application
- IF 1: 100-1:500, ELISA 1:5000-1:240000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.7 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- VNN1 (Vanin 1 (VNN1))
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Autre désignation
- VNN1
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Sujet
- This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
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UniProt
- O95497
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Antigène
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