T-Box 1 anticorps

N° du produit ABIN7254388

Détail du produit anti-T-Box 1 anticorps

Antigène: T-Box 1 (TBX1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Box 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human TBX1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur T-Box 1

Antigène: T-Box 1 (TBX1)

Autre désignation: TBX1 (TBX1 Produits)

Synonymes: anticorps CAFS, anticorps CTHM, anticorps DGCR, anticorps DGS, anticorps DORV, anticorps TBX1C, anticorps TGA, anticorps VCFS, anticorps mp:zf637-3-000616, anticorps zgc:136724, anticorps TBX1, anticorps dgs, anticorps tga, anticorps cafs, anticorps cthm, anticorps dgcr, anticorps dorv, anticorps vcfs, anticorps tbx1c, anticorps xtbx1, anticorps tbx1, anticorps T-box 1, anticorps T-box 1 S homeolog, anticorps T-box 1 L homeolog, anticorps TBX1, anticorps Tbx1, anticorps tbx1, anticorps tbx1.S, anticorps tbx1.L

Sujet: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 43 kDa

UniProt: O43435

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation