GANAB
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cobaye, Cheval, Lapin
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC 1:50-1:100, ELISA 1:2000-1:5000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.72 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
GANAB
(Glucosidase, Alpha, Neutral AB (GANAB))
Autre désignation
GANAB
Sujet
Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.