YBX1 anticorps

N° du produit ABIN7254631

Cet anticorps Lapin Polyclonal détecte spécifiquement YBX1 dans IHC et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour YBX1 anticorps (ABIN7254631)

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YBX1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-YBX1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human YBX1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur YBX1

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Autre désignation: YBX1

Sujet: This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation