TPMT anticorps

N° du produit ABIN7255179

Cet anticorps Lapin Polyclonal détecte spécifiquement TPMT dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TPMT anticorps (ABIN7255179)

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPMT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TPMT anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human TPMT (NP_000358.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TPMT

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Autre désignation: TPMT

Sujet: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

Poids moléculaire:

Observed_MW: 28 kDa

Calculated_MW: 28 kDa

ID gène: 7172

UniProt: P51580