Septin 5 anticorps

N° du produit ABIN7256500

Détail du produit anti-Septin 5 anticorps

Antigène: Septin 5 (SEPT5)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 5 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human 44079 (NP_002679.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Septin 5

Antigène: Septin 5 (SEPT5)

Autre désignation: SEPT5 (SEPT5 Produits)

Synonymes: anticorps sept5, anticorps fj37h04, anticorps zgc:73218, anticorps wu:fj37h04, anticorps SEPT5, anticorps Cdcrel-1, anticorps Cdcrel1, anticorps Pnutl1, anticorps 5-Sep, anticorps CDCrel-1A, anticorps CDCREL, anticorps CDCREL-1, anticorps CDCREL1, anticorps H5, anticorps HCDCREL-1, anticorps PNUTL1, anticorps septin 5a, anticorps septin 5, anticorps sept5a, anticorps SEPT5, anticorps sept5, anticorps Sept5

Sujet: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

ID gène: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis