Peroxiredoxin 3 anticorps
Aperçu rapide pour Peroxiredoxin 3 anticorps (ABIN7256588)
Antigène
Voir toutes Peroxiredoxin 3 (PRDX3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human PRDX3 (NP_006784.1).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IF 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Peroxiredoxin 3 (PRDX3)
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Autre désignation
- PRDX3
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Sujet
- This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.
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Poids moléculaire
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Observed_MW: 28 kDa
Calculated_MW: 25 kDa/27 kDa
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ID gène
- 10935
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UniProt
- P30048
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Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Antigène
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