C10orf2 anticorps
Aperçu rapide pour C10orf2 anticorps (ABIN7256978)
Antigène
Voir toutes C10orf2 (C10ORF2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide of human C10orf2 (NP_068602.2).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
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Autre désignation
- C10orf2
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Sujet
- This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Poids moléculaire
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Observed_MW: 77 kDa
Calculated_MW: 60 kDa/66 kDa/77 kDa
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ID gène
- 56652
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UniProt
- Q96RR1
Antigène
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