MDFI anticorps
Aperçu rapide pour MDFI anticorps (ABIN7257327)
Antigène
Voir toutes MDFI AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human MDFI (NP_005577.1).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MDFI (MyoD Family Inhibitor (MDFI))
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Autre désignation
- MDFI
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Sujet
- This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
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Poids moléculaire
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Observed_MW: 35 kDa
Calculated_MW: 25 kDa
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ID gène
- 4188
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UniProt
- Q99750
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Pathways
- Maintenance of Protein Location
Antigène
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