Reticulon 3 anticorps
Aperçu rapide pour Reticulon 3 anticorps (ABIN7258404)
Antigène
Voir toutes Reticulon 3 (RTN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide of human RTN3 (NP_006045.1).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Reticulon 3 (RTN3)
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Autre désignation
- RTN3
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Sujet
- This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
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Poids moléculaire
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Observed_MW: 26 kDa
Calculated_MW: 23 kDa/25 kDa/26 kDa/27 kDa/100 kDa/110 kDa/112 kDa
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ID gène
- 10313
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UniProt
- O95197
Antigène
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