YTHDF2 anticorps

N° du produit ABIN7258512

Cet anticorps Lapin Polyclonal détecte spécifiquement YTHDF2 dans IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour YTHDF2 anticorps (ABIN7258512)

Antigène: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YTHDF2 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-YTHDF2 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human YTHDF2 (NP_057342.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur YTHDF2

Antigène: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Autre désignation: YTHDF2

Sujet: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

ID gène: 51441

UniProt: Q9Y5A9