UNC13B anticorps

N° du produit ABIN7258666

L’anticorps Lapin Polyclonal anti-UNC13B a été validé pour WB et IF. Il convient pour détecter UNC13B dans des échantillons de Humain et Souris.

Aperçu rapide pour UNC13B anticorps (ABIN7258666)

Antigène: UNC13B (Unc-13 Homolog B (UNC13B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC13B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-UNC13B anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human UNC13B (NP_006368.3).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UNC13B

Antigène: UNC13B (Unc-13 Homolog B (UNC13B))

Autre désignation: UNC13B

Sujet: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

Poids moléculaire:

Observed_MW: 210 kDa

Calculated_MW: 180 kDa/182 kDa

ID gène: 10497

UniProt: O14795

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis