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UNC13B anticorps

UNC13B Reactivité: Humain, Souris WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7258666
  • Antigène Voir toutes UNC13B Anticorps
    UNC13B (Unc-13 Homolog B (UNC13B))
    Reactivité
    • 31
    • 18
    • 3
    Humain, Souris
    Hôte
    • 40
    • 3
    • 1
    Lapin
    Clonalité
    • 42
    • 2
    Polyclonal
    Conjugué
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UNC13B est non-conjugé
    Application
    • 32
    • 26
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human UNC13B (NP_006368.3).
    Isotype
    IgG
    Top Product
    Discover our top product UNC13B Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    UNC13B (Unc-13 Homolog B (UNC13B))
    Autre désignation
    UNC13B (UNC13B Produits)
    Synonymes
    anticorps MUNC13, anticorps UNC13, anticorps Unc13h2, anticorps UNC13B, anticorps Munc13-2, anticorps Munc13-1, anticorps Unc13a, anticorps Unc13h1, anticorps unc-13 homolog B, anticorps unc-13 homolog B (C. elegans), anticorps UNC13B, anticorps Unc13b
    Sujet
    This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
    Poids moléculaire

    Observed_MW: 210 kDa

    Calculated_MW: 180 kDa/182 kDa

    ID gène
    10497
    UniProt
    O14795
    Pathways
    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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