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Glutathione Peroxidase 2 anticorps

GPX2 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7009224
  • Antigène Voir toutes Glutathione Peroxidase 2 (GPX2) Anticorps
    Glutathione Peroxidase 2 (GPX2)
    Reactivité
    • 14
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 14
    • 1
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    Cet anticorp Glutathione Peroxidase 2 est non-conjugé
    Application
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human GPX2 (NP_002074.2).
    Isotype
    IgG
    Top Product
    Discover our top product GPX2 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Glutathione Peroxidase 2 (GPX2)
    Autre désignation
    GPX2 (GPX2 Produits)
    Synonymes
    anticorps ATGPX2, anticorps GLUTATHIONE PEROXIDASE, anticorps T9H9.9, anticorps T9H9_9, anticorps glutathione peroxidase 2, anticorps GI-GPx, anticorps GPRP, anticorps GPRP-2, anticorps GPx-2, anticorps GPx-GI, anticorps GSHPX-GI, anticorps GSHPx-2, anticorps LOC100136264, anticorps GSHPx-GI, anticorps GPX-GI, anticorps glutathione peroxidase 2, anticorps glutathione peroxidase 1, anticorps GPX2, anticorps gpx1, anticorps Gpx2, anticorps LELG_01052
    Sujet
    The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
    ID gène
    2877
    UniProt
    P18283
    Pathways
    Thyroid Hormone Synthesis
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