GABRD anticorps
Aperçu rapide pour GABRD anticorps (ABIN7009232)
Antigène
Voir toutes GABRD AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Attributs du produit
- Polyclonal Antibody
-
Purification
- Affinity purification
-
Immunogène
- Recombinant fusion protein of human GABRD (NP_000806.2).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- GABRD (GABA A Receptor delta (GABRD))
-
Autre désignation
- GABRD
-
Sujet
- Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
-
Poids moléculaire
-
Observed_MW: 68 kDa
Calculated_MW: 50 kDa
-
ID gène
- 2563
-
UniProt
- O14764
Antigène
-