PIN1 anticorps
Aperçu rapide pour PIN1 anticorps (ABIN7260173)
Antigène
Voir toutes PIN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Attributs du produit
- Polyclonal Antibody
-
Purification
- Affinity purification
-
Immunogène
- Recombinant fusion protein of human PIN1 (NP_006212.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
-
Autre désignation
- PIN1
-
Sujet
- Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.
-
Poids moléculaire
-
Observed_MW: 18 kDa
Calculated_MW: 18 kDa
-
ID gène
- 5300
-
UniProt
- Q13526
Antigène
-