CBX3 anticorps

N° du produit ABIN7260333

Détail du produit anti-CBX3 anticorps

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificité: This antibody ist KO validated.

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Classe de qualité: KO Validated

Immunogène: Recombinant fusion protein of human CBX3 (NP_009207.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: CBX3 (CBX3 Produits)

Synonymes: anticorps HECH, anticorps HP1-GAMMA, anticorps HP1Hs-gamma, anticorps Hp1-gamma, anticorps HP1g, anticorps M32, anticorps cbx3, anticorps cbx3a, anticorps xhp1g, anticorps wu:fb61b02, anticorps zgc:153397, anticorps chromobox 3, anticorps chromobox 3 L homeolog, anticorps chromobox protein homolog 3 pseudogene, anticorps chromobox homolog 3a (HP1 gamma homolog, Drosophila), anticorps CBX3, anticorps Cbx3, anticorps cbx3.L, anticorps LOC100355282, anticorps cbx3a

Sujet: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Poids moléculaire:

Observed_MW: 23 kDa

Calculated_MW: 20 kDa

ID gène: 11335

UniProt: Q13185