PRNP anticorps

N° du produit ABIN7260569

Détail du produit anti-PRNP anticorps

Antigène: PRNP (Prion Protein (PRNP))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRNP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PRNP (NP_001073592.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRNP

Antigène: PRNP (Prion Protein (PRNP))

Autre désignation: PRNP (PRNP Produits)

Synonymes: anticorps ASCR, anticorps AltPrP, anticorps CD230, anticorps CJD, anticorps GSS, anticorps KURU, anticorps PRIP, anticorps PrP, anticorps PrP27-30, anticorps PrP33-35C, anticorps PrPc, anticorps p27-30, anticorps Prn, anticorps Prn-p, anticorps prp, anticorps cjd, anticorps prion, anticorps prp(c), anticorps MGC84114, anticorps PRP, anticorps PRPC, anticorps Prp, anticorps SIP, anticorps PRNP, anticorps AA960666, anticorps AI325101, anticorps PrP, anticorps PrPC, anticorps PrPSc, anticorps Prn-i, anticorps Sinc, anticorps prP27-30, anticorps prP33-35C, anticorps PrP-1, anticorps PrP1, anticorps prnprs1, anticorps stPrP-1, anticorps zgc:123004, anticorps prion protein, anticorps prion protein S homeolog, anticorps prion protein b, anticorps PRNP, anticorps Prnp, anticorps prnp.S, anticorps prnpb

Sujet: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 20-30 kDa

Calculated_MW: 8 kDa/26 kDa/27 kDa

ID gène: 5621

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation