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PGC anticorps

PGC Reactivité: Humain, Rat, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7260655
  • Antigène Voir toutes PGC Anticorps
    PGC (Pepsinogen C (PGC))
    Reactivité
    • 62
    • 16
    • 11
    • 2
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 54
    • 18
    • 2
    Lapin
    Clonalité
    • 58
    • 16
    Polyclonal
    Conjugué
    • 25
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PGC est non-conjugé
    Application
    • 40
    • 24
    • 18
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide of human Pepsinogen II (NP_001159896.1).
    Isotype
    IgG
    Top Product
    Discover our top product PGC Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PGC (Pepsinogen C (PGC))
    Autre désignation
    Pepsinogen II (PGC Produits)
    Synonymes
    anticorps PEPC, anticorps PGII, anticorps 2210410L06Rik, anticorps Upg-1, anticorps Upg1, anticorps CPGC, anticorps gastricsin, anticorps PG1, anticorps Pg-1, anticorps PGNC, anticorps PGC, anticorps Gastricsin, anticorps progastricsin (pepsinogen C), anticorps progastricsin, anticorps PGC, anticorps Pgc
    Sujet
    This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
    Poids moléculaire

    Observed_MW: 45-50 kDa

    Calculated_MW: 34 kDa/42 kDa

    ID gène
    5225
    UniProt
    P20142
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