RBM15 anticorps

N° du produit ABIN7261163

Détail du produit anti-RBM15 anticorps

Antigène: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM15 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RBM15 (NP_001188474.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RBM15

Antigène: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Autre désignation: RBM15 (RBM15 Produits)

Synonymes: anticorps MGC83913, anticorps im:7139999, anticorps OTT, anticorps OTT1, anticorps SPEN, anticorps C230088J01Rik, anticorps mKIAA1438, anticorps RNA binding motif protein 15, anticorps RNA binding motif protein 15 S homeolog, anticorps RBM15, anticorps rbm15.S, anticorps rbm15, anticorps Rbm15

Sujet: RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5' translocation partner of the MAL gene in t(1,22)(p13,q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.

Poids moléculaire:

Observed_MW: 120 kDa

Calculated_MW: 99 kDa/104 kDa/106 kDa/107 kDa

ID gène: 64783

UniProt: Q96T37