MCM10 anticorps

N° du produit ABIN7261385

Cet anticorps anti-MCM10 est un anticorps Lapin Polyclonal détectant MCM10 dans IF. Adapté pour Humain et Souris.

Aperçu rapide pour MCM10 anticorps (ABIN7261385)

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM10 est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-MCM10 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MCM10 (NP_877428.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCM10

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Autre désignation: MCM10

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

ID gène: 55388

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication