APLP2 anticorps

N° du produit ABIN7261415

Cet anticorps Lapin Polyclonal détecte spécifiquement APLP2 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour APLP2 anticorps (ABIN7261415)

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-APLP2 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human APLP2 (NP_001135750.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur APLP2

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Autre désignation: APLP2

Sujet: This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire:

Observed_MW: 87 kDa

Calculated_MW: 59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa

ID gène: 334

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour