LITAF anticorps

N° du produit ABIN7261431

Cet anticorps Lapin Polyclonal détecte spécifiquement LITAF dans WB et IHC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour LITAF anticorps (ABIN7261431)

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LITAF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: KO Validated

Détail du produit anti-LITAF anticorps

Specificité: This antibody ist KO validated.

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human LITAF (NP_004853.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LITAF

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Autre désignation: LITAF

Sujet: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Poids moléculaire:

Observed_MW: 20 kDa

Calculated_MW: 15 kDa/17 kDa/23 kDa

ID gène: 9516

UniProt: Q99732

Pathways: Cellular Response to Molecule of Bacterial Origin