COMP anticorps
Aperçu rapide pour COMP anticorps (ABIN7261762)
Antigène
Voir toutes COMP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human COMP (NP_000086.2).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IF 1:10-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- COMP (Cartilage Oligomeric Matrix Protein (COMP))
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Autre désignation
- COMP
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Sujet
- The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
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Poids moléculaire
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Observed_MW: 110 kDa
Calculated_MW: 77 kDa/82 kDa
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ID gène
- 1311
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UniProt
- P49747
Antigène
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