KLF4 anticorps
Aperçu rapide pour KLF4 anticorps (ABIN7262523)
Antigène
Voir toutes KLF4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human KLF4 (NP_004226.3).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
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Autre désignation
- KLF4
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Sujet
- This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Poids moléculaire
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Observed_MW: 50 kDa
Calculated_MW: 6 kDa/12 kDa/45 kDa/51 kDa/54 kDa
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ID gène
- 9314
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UniProt
- O43474
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Pathways
- Peptide Hormone Metabolism, Stem Cell Maintenance
Antigène
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