Deoxyguanosine Kinase anticorps

N° du produit ABIN7262793

L’anticorps Lapin Polyclonal anti-Deoxyguanosine Kinase a été validé pour IHC. Il convient pour détecter Deoxyguanosine Kinase dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Deoxyguanosine Kinase anticorps (ABIN7262793)

Antigène: Deoxyguanosine Kinase (DGUOK)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Deoxyguanosine Kinase est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Deoxyguanosine Kinase anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human DGUOK (NP_550438.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Deoxyguanosine Kinase

Antigène: Deoxyguanosine Kinase (DGUOK)

Autre désignation: DGUOK

Sujet: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

ID gène: 1716

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process